is generated by the Genomic and Pharmacology Facilit, DTB, CCR, NCI, NIH. It is a database and query tool designed for the cancer research community to facilitate integration and study of molecular and pharmacological data for the NCI-60 cancerous cell lines. The NCI-60, a panel of 60 diverse human cancer cell lines used by the Developmental Therapeutics Program of the U.S. National Cancer Institute to screen over 100,000 chemical compounds and natural products (since 1990).

To cite the tool, the primary literature references are (Shankavaram, BMC Genomic, 2009 and Reinhold, Cancer Res, 2012).

Press articles reviewing CellMiner may be accessed here (Cancer Discovery) (CCR Connections) (NCI press release) (FierceBiotechIT).

Press articles reviewing the Exome data set may be accessed here (Time Magazine) (NPR) (Forbes) (Los Angeles Times) (U.S. News Health) (GenomeWeb Daily News).

Subsequent builds will include additional molecular data sets and integrative capabilities.

Release Notes

Version 2022.1 - 03/10/2022
  • Gene version: Hg19 from NCBI
  • DTP drug pull date: 03/01/2022
  • Database version: v2.8.1
  • Refactored code for drug z-score database batch scripts.
Historical Release Notes

How to find the information you need in CellMiner using the above tabs

Other Useful Pages Resources

For other bioinformatic tools and database resources from GBG go to the Discover website home page.

For additional drug, dataset and molecular target data see the NCI Developmental Therapeutics Program site.

For access to our Cytogenetics (spectral karyotyping) of the NCI-60, type 'NCI-60' in the NCBI's sky database search page.

CellMiner Development Team

Jeffrey Yang-Hsin Wang, Sudhir Varma, William Reinhold and Yves Pommier prior contributors