p53-MdmX-Mdm2 network model

The best way to view the map is on a PC with IE with the Adobe SVG viewer. For your browser type only our static map is available.

Sohyoung Kim, Mirit I. Aladjem, Geoffrey B. McFadden, Kurt W. Kohn

Implemented by : Margot Sunshine

To lay the foundation of a model, we first assembled the known molecular interactions among p53, Mdm2, and MdmX in the form of a heuristic MIM (Figure 1) using the previously described notation (Kohn, 1999, 2001; Kohn et al., 2006). The heuristic MIM organizes information from which explicit models (Figure 2) for simulations can be extracted and portrayed as an explicit MIM (Kohn 2001).

Map symbols       Map Navigation