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Regulation of hypoxia-responsive genes
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Regulation of hypoxia-responsive genes

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Kurt W. Kohn, Joseph Riss, Mirit Aladjem and Yves Pommier

Implemented by : Margot Sunshine, Hong Cao and David Kane

This molecular interaction map depicts the regulatory network that inhibits transcription in the presence of normal oxygen levels and switches HIF-mediated transcription on when oxygen levels are reduced. An analysis of the hypoxia-induced regulatory switch can be accessed here

A glossary of the molecules participating in the hypoxia-induced response is available here
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